It’s a simple idea, yet powerful.
If you are drawing, photographing or painting a particular subject, consider a different angle other than a simple straight on view. For a portrait, try it from one side or the other, tilt the head slightly, etc. When depicting a scene, consider a low angle, or maybe even an overhead angle. Think of ways to add interest. The more interesting a picture looks, the more likely it is to stand out in the crowd. Too many people pick a centered straight on view for a portrait rather than a three quarter view, that can look flat and uninteresting.
Different angles can also help convey mood and enhance your message.